COX4NB蛋白抗体
规格:1mg/1ml
英文名: COX4NB
别名: C16orf4; COX4 neighbor; Neighbor of COX4; COX4AL; Cox4nb; CX4NB_HUMAN; Neighbor of COX4; NOC4; EMC8; C16orf2; Protein FAM158B.
分子量: 24kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human COX4NB
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位:细胞浆
COX4NB蛋白抗体产品介绍:background: COX4NB is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn’s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric COX4NB蛋白抗体region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. Subunit: Component of the ER membrane protein complex (EMC). Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in liver, pancreas, heart, lung, kidney, brain, skeletal muscle, and placenta. Expression levels are highest in pancreas and moderate in heart, skeletal muscle, and placenta. COX4NB蛋白抗体Similarity: Belongs to the EMC8/EMC9 family. Database links: UniProtKB/Swiss-Prot: O43402.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
COX4NB蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid