丝氨酸/苏氨酸蛋白磷酸酶3B抗体
规格:1mg/1ml
英文名: PP4R3B
别名: Protein Phosphatase 4, Regulatory Subunit 3 Beta; smk1; FLFL2; PPP4R3B; PSY2; Serine/threonine-protein phosphatase 4 regulatory subunit 3B; SMEK 2; SMEK homolog 2; SMEK homolog 2 suppressor of mek1 (D
分子量: 97kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SMEK2/PP
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核 细胞浆
丝氨酸/苏氨酸蛋白磷酸酶3B抗体产品介绍:background: SMEK2 contains a WH1 domain. There are five named isoforms produced by alternative splicing. Mapping of a diet-induced hypercholesterolemia locus (Dihc2) in rats identified SMEK2 as a strong candidate for responsiveness to dietary cholesterol. Function: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Subunit: Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complex PPP4C-PPP4R2-PPP4R3B. Subcellular Location: 丝氨酸/苏氨酸蛋白磷酸酶3B抗体Cytoplasm. Cytoskeleton. Centrosome. Nucleus. Note: In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions. Tissue Specificity: Moderately expressed in tissues and specific brain regions examined. Similarity: Belongs to the SMEK family. Contains 1 WH1 domain. Database links: UniProtKB/Swiss-Prot: Q5MIZ7.2 Important丝氨酸/苏氨酸蛋白磷酸酶3B抗体 Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产丝氨酸/苏氨酸蛋白磷酸酶3B抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 发育生物学 信号转导 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid