DPY19L2蛋白抗体
规格：1mg/1ml
英文名： DPY19L2
别名： D19L2_HUMAN; dpy 19 like 2; dpy 19 like 2 (C. elegans); Dpy 19 like protein 2; Dpy-19-like protein 2; dpy19; DPY19L2; FLJ32949; FLJ36166; Protein dpy 19 homolog 2; Protein dpy-19 homolog 2.
分子量： 87kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DPY19L2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：
DPY19L2蛋白抗体产品介绍：background: Required during spermatogenesis for sperm head elongation and acrosome formation. Function: Required during spermatogenesis for sperm head elongation and acrosome formation. Subunit: Membrane; Multi-pass membrane protein (Potential). Subcellular Location: Involvement in disease：Defects in DPY19L2 are a cause of globozoospermia (GLOBZOOS) . An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome. In the most severe cases the acrosome is totally absent. Globozoospermia is also characterized by abnormal nuclear shape as well as abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of GLOBZOOS. Tissue Specificity: Widely expressed with high DPY19L2蛋白抗体expression in testis. DISEASE: Defects in DPY19L2 are the cause of spermatogenic failure type 9 (SPGF9) [MIM:613958]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoonDPY19L2蛋白抗体. Note=Deletions in DPY19L2 are probably the major cause of SPGF9. Similarity: Belongs to the dpy-19 family. Database links: UniProtKB/Swiss-Prot: Q6NUT2.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产DPY19L2蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid