P因子/备解素抗体
规格：1mg/1ml
英文名： Properdin
别名： BFD; CFP; Complement factor P; Complement factor properdin; Factor P; PFC; PFD; PROP_HUMAN; Properdin; Properdin P factor complement.
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Properdi
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：分泌型蛋白
P因子/备解素抗体产品介绍：background: A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Involvement in disease:Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). Function: A positive regulator of the P因子/备解素抗体alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Subcellular Location: Secreted DISEASE: Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibilityP因子/备解素抗体 to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). Similarity: Contains 6 TSP type-1 domains. Database links: UniProtKB/Swiss-Prot: P27918.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
P因子/备解素抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid