GTP酶IMAP家族成员3抗体
规格:1mg/1ml
英文名: GIMAP3
别名: GTPase, IMAP family member 3 pseudogene; Ian4; Gimap5; 2010110D23Rik; GIMAP 3; GIMAP3; GTPase IMAP family member 3; GTPase of the immune associated protein 3; Immune associated nucleotide 4; Immunity
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from mouse GIMAP3
交叉反应:Mouse, Rat,
细胞定位:细胞浆 细胞膜
GTP酶IMAP家族成员3抗体产品介绍:background: GIMAP3p is a murine mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The IAN/GIMAP family consists of GTP-binding proteins that share a unique primary structure and whose expression is finely regulated by T-cell receptor signals. Recent studies have shown that IAN/GIMAP family proteins crucially regulate the survival of T cells during development, selection and homeostasis, and are possibly linked to the onset of T-lymphopenia, leukemia and autoimmunity. IAN/GIMAP family proteins might also take part in mitochondrial regulation GTP酶IMAP家族成员3抗体of lymphocyte apoptosis by interacting with Bcl-2 family proteins. The human GIMAP (GTPase of the immunity-associated protein) gene family includes seven functional members residing on (human) chromosome 7q36.1 and one pseudogene GTP酶IMAP家族成员3抗体(hGIMAP3). Subcellular Location: Mitochondrion outer membrane; Single-pass type IV membrane protein. Tissue Specificity: May be restricted to certain hematopoietic cells. Similarity: Belongs to the IAN GTP-GTP酶IMAP家族成员3抗体binding protein family. Database links: UniProtKB/Swiss-Prot: Q99MI6.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid