GTP酶IMAP家族成员8抗体
规格:1mg/1ml
英文名: GIMAP8
别名: GTPase IMAP family member 8; hIAN6; Human immune associated nucleotide 6; IAN9; IANT; Immune associated nucleotide; Immune-associated nucleotide-binding protein 9; Protein IanT; GIMA8_HUMAN.
分子量: 75kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GIMAP8
交叉反应:Human, Mouse, Rat, Horse, Rabbit,
细胞定位:细胞浆
GTP酶IMAP家族成员8抗体产品介绍:background: The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP8, also known as IAN9 (immune-associated nucleotide-binding protein 9) or IANT, is a 665 amino acid protein that localizes to Golgi apparatus, Endoplasmic reticulum and mitochondria. Suggested to have an anti-apoptotic effect on the immune system, GIMAP8 plays a role in infection response and is encoded by a gene that maps to human chromosome 7q36.1. Chromosome 7 GTP酶IMAP家族成员8抗体houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections (By similarity). Subcellular Location: Endoplasmic reticulum (By similarity). Golgi apparatusGTP酶IMAP家族成员8抗体 (By similarity). Mitochondrion (By similarity). Similarity: Belongs to the IAN GTP-binding protein family. Database links: UniProtKB/Swiss-Prot: Q8ND71.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产GTP酶IMAP家族成员8抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid