DYDC1蛋白抗体
规格:1mg/1ml
英文名: DYDC1
别名: DPY30 domain-containing protein 1; DPY30D1; DYDC1; DYDC1_HUMAN; RSD 9; RSD9.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DYDC1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
产DYDC1蛋白抗体品介绍:background: The Dumpy-30 (DPY-30) protein was first described in C. elegans, in which it is involved in dosage compensation of sex chromosomes. Conserved from yeast to humans, the DPY-30 family is involved in gene expression and chromatin modification, specifically histone methylation. DPY-30 and closely related proteins contain a short motif that is related to the dimerization motif in the regulatory subunit of protein kinase A (PKA), which consists of two ?helices that form a four-helix bundle during dimerization. As a member of the DPY-30 family, DYDC1 (DPY30 domain-containing protein 1), also known as DPY30D1 and RSD9, is a 177 aminoDYDC1蛋白抗体 acid protein that binds to Endophilin III and plays a crucial role during acrosome biogenesis. DYDC1 is specifically expressed in brain and testis and accumulates in the acrosome area during spermatogenesis. Knockdown of DYDC1 mRNA results in disruption of acrosome formation and spermatid differentiation. Function: Plays a crucial role during acrosome biogenesis. Subunit: Interacts with SH3GL3. Tissue DYDC1蛋白抗体Specificity: Brain and testis. Accumulates during late stage of spermiogenesis. Similarity: Belongs to the dpy-30 family. Database links: UniProtKB/Swiss-Prot: Q8WWB3.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DYDC1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 发育生物学 神经生物学
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid