短链脱氢酶/还原酶家族4抗体
规格：1mg/1ml
英文名： DHRS4
别名： NDRD; RRD; AI043103; AI790593; Carbonyl reductase; CR; D14Ucla2; Dehydrogenase/reductase SDR family member 4; Dhrs4; DHRS4_HUMAN; humNRDR antibody NADPH dependent carbonyl reductase/NADP retinol dehyd
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DHRS4
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
短链脱氢酶/还原酶家族4抗体产品介绍：background: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones. Tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues. Function: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine,短链脱氢酶/还原酶家族4抗体 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity). Subunit: Homotetramer (By similarity). Subcellular Location: Peroxisome. Note=Isoform 1 is peroxisomal, while isoform 4 is not. Isoform 7: Nucleus. Tissue Specificity: Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in短链脱氢酶/还原酶家族4抗体 some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Database links: UniProtKB/Swiss-Prot: Q9BTZ2.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
短链脱氢酶/还原酶家族4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid