GTP酶IMAP家族成员1抗体
规格：1mg/1ml
英文名： GIMAP1
别名： GIMA1_HUMAN; GIMAP1; GTPase IMAP family member 1; hIMAP1; Immunity-associated protein 1.
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GIMAP1
交叉反应：Human, Mouse, Rat, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
GTP酶IMAP家族成员1抗体产品介绍：background: The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP1 (GTPase, IMAP family member 1), also known as IMAP1 (immunity-associated protein 1), HIMAP1 or IMAP38, is a 306 amino acid single-pass type IV membrane protein of the endoplasmic reticulum (ER) belonging to the GIMAP family. Encoded by a gene located on human chromosome 7, GIMAP1 is expressed primarily in spleen with lower levels found in lymph node. Chromosome GTP酶IMAP家族成员1抗体7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: May regulate lymphocyte survival. GTP酶IMAP家族成员1抗体Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity). Subcellular Location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane (By similarity). Tissue Specificity: Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Similarity: Belongs to the IAN GTP-binding protein family. Database links: UniProtKB/Swiss-Prot: Q8WWP7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GTP酶IMAP家族成员1抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid