FRMD8蛋白抗体
规格:1mg/1ml
英文名: FRMD8
别名: FERM domain containing protein 8; FKSG44; FRMD8_HUMAN.
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FRMD8
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位:
FRMD8蛋白抗体产品介绍:background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD8 (FERM domain-containing protein 8), also known as FKSG44, is a 464 amino acid protein containing one FERM domain. Existing as two alternatively spliced isoforms, the gene encoding FRMD8 maps to human chromosome 11q13.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and isFRMD8蛋白抗体 considered a gene and disease association dense chromosome. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick diseaseFRMD8蛋白抗体, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. Similarity: Contains 1 FERM domain. Database links: UniProtKB/Swiss-Prot: Q9BZ67.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FRMD8蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid