丝氨酸/苏氨酸蛋白激酶SAD-B抗体
规格：1mg/1ml
英文名： BRSK1
别名： BR serine/threonine kinase 1; BR serine/threonine protein kinase 1; BR serine/threonine-protein kinase 1; Brain-specific serine/threonine-protein kinase 1; BRSK 1; Brsk1; BRSK1_HUMAN; Protein kinase S
分子量： 86kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BRSK1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：细胞核 细胞浆 细胞膜
丝氨酸/苏氨酸蛋白激酶SAD-B抗体产品介绍：background: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle. Subcellular Location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome.丝氨酸/苏氨酸蛋白激酶SAD-B抗体 Cell junction, synapse. Note=Localizes to synaptic vesicles in neurons. Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage. Tissue Specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle. Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr 丝氨酸/苏氨酸蛋白激酶SAD-B抗体protein kinase family. SNF1 subfamily. Contains 1 protein kinase domain. Contains 1 UBA domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝氨酸/苏氨酸蛋白激酶SAD-B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid