周期素D结合蛋白1抗体
规格：1mg/1ml
英文名： CCNDBP1
别名： Maternal inhibition of differentiation; SECC 8; SSEC 8; CCDB1_HUMAN; CCNDBP 1; Ccndbp1; Cyclin D type binding protein 1; Cyclin-D1-binding protein 1; D type cyclin interacting protein 1; DIP 1; DIP1;
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCNDBP1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
周期素D结合蛋白1抗体产品介绍：background: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas. Function: May negatively regulate cell cycle progression. May actat least in part via inhibition of the cyclin-D1/CDK4 complex,thereby preventing phosphorylation of RB1 and blockingE2F-dependent transcription. Subunit: Interacts with周期素D结合蛋白1抗体 CCND1 and GRAP2. May also interact withCOPS5, RPLP0, SIRT6, SYF2 and TCF3. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed. Expression isdown-regulated in a variety of tumor types including breast, colon,prostate and rectal tumors, and is up-regulated in certain hepaticcarcinomas. Post-translational modifications: Phosphorylated. Similarity: Belongs to the CCNDBP1 family周期素D结合蛋白1抗体. Database links: UniProtKB/Swiss-Prot: O95273.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
周期素D结合蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid