**细胞相关AF4样蛋白抗体
规格：1mg/1ml
英文名： AFF4
别名： Alf4; Laf4; MGC107469; AF4/FMR2 family member 4; AF5Q31; ALL1 fused gene from chromosome 5q31; HSPC092; Lymphoid nuclear protein related to AF4 like; Major CDK9 elongation factor associated protein; M
分子量： 127kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AFF4
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
**细胞相关AF4样蛋白抗体产品介绍：background: May play a role in transcriptional regulation. Component of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor b (P-TEFb). Function: May play a role in transcriptional regulation. Subunit: Component of the cyclin-dependent kinase pair(CDK9/cyclin-T1) complex, also called positive transcriptionelongation factor b (P-TEFb). Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously expressed. Strongly expressed inheart, placenta, skeletal muscle, pancreas and to a lower extent inbrain. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or**细胞相关AF4样蛋白抗体 ATR. [DISEASE] Note=A chromosomal aberration involving AFF4 is found inacute lymphoblastic leukemia (ALL). Insertion ins(5;11)(q31;q13q23)that forms a MLL-AFF4 fusion protein. Similarity: Belongs to the AF4 family. Gene ID: 27125 Database links: Entrez Gene: 27125 Human Entrez Gene: 93736 Mouse Entrez Gene: 303132 Rat Omim: 604417 Human SwissProt: Q9UHB7 Human SwissProt: **细胞相关AF4样蛋白抗体Q9ESC8 Mouse Unigene: 519313 Human Unigene: 395281 Mouse Unigene: 17594 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**细胞相关AF4样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid