周期素T2抗体
规格:1mg/1ml
英文名: Cyclin T2
别名: CCNT2; CCNT2_HUMAN; Cyclin-T2; CycT2; FLJ90560; MGC134840.
分子量: 80kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Cyclin T
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核
周期素T2抗体产品介绍:background: Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). Function: Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA周期素T2抗体 polymerase II (RNAP II). Subunit: Associates with CDK9 to form P-TEFb. Isoform 1 and isoform 2 interact with HIV-2 and SIV Tat. Does not bind efficiently to the transactivation domain of the HIV-1 Tat. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously 周期素T2抗体expressed. Similarity: Belongs to the cyclin family. Cyclin C subfamily. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
周期素T2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit