上皮分泌型FAM3C蛋白抗体
规格：1mg/1ml
英文名： FAM3C
别名： Fam3c; FAM3C_HUMAN; family with sequence similarity 3, member C; GS3786; ILEI; Interleukin-like EMT inducer; Predicted osteoblast protein; Protein FAM3C.
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM3C
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：细胞浆 分泌型蛋白
上皮分泌型FAM3C蛋白抗体产品介绍：background: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with 上皮分泌型FAM3C蛋白抗体the invasion, metastasis and survival in a variety of cancers. Function: May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition. Subcellular Location: Secreted. Cytoplasmic vesicle. Note=Cytoplasmic in some cancer cells. 上皮分泌型FAM3C蛋白抗体Tissue Specificity: Present in most secretory epithelia (at protein level). Similarity: Belongs to the FAM3 family. Database links: UniProtKB/Swiss-Prot: Q92520.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
上皮分泌型FAM3C蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid