神经氨酸酶4抗体
规格：1mg/1ml
英文名： NEU4
别名： N acetyl alpha neuraminidase 4; Neuraminidase 4; Sialidase 4; NEUR4_HUMAN.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NEU4 (13
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆 细胞膜
神经氨酸酶4抗体产品介绍：background: NEU4 belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Function: May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid (4-MU-NANA or 4MU-NeuAc). Has a broad substrate specificity being active on glycoproteins, oligosaccharides and sialylated glycolipids. Subcellular Location: Isoform 1: Membrane;神经氨酸酶4抗体 Peripheral membrane protein. Isoform 2: Lysosome lumen. Tissue Specificity: Ubiquitous with higher expression in heart, skeletal muscle, liver and placenta. Post-translational modifications: According to PubMed:15213228, phosphorylation of mannose residues may ensure efficient transport of isoform 2 to the lysosomes via the mannose 6-phosphate receptor. Isoform 2 is glycosylated (PubMed:15213228).神经氨酸酶4抗体 Similarity: Belongs to the glycosyl hydrolase 33 family. Contains 3 BNR repeats. Database links: UniProtKB/Swiss-Prot: Q8WWR8.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经氨酸酶4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid