S100A2抗体
规格:1mg/1ml
英文名: S100 alpha 2
别名: S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN
分子量: 11kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human S100 alp
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Goat, Cat, ,lizard
细胞定位:
S100A2抗体产品介绍:background: The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpressionS100A2抗体 of this gene have been implicated in breast cancer. Function: May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth. Subunit: Homodimer. Interacts with FKBP4. Tissue Specificity: A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes. Similarity: Belongs to the S-100 family S100A2抗体Contains 2 EF-hand domains. Database links: UniProtKB/Swiss-Prot: P29034.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
S100A2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞周期蛋白 结合蛋白 细胞分化
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid