有丝分裂相关蛋白INSC抗体
规格:1mg/1ml
英文名: INSC
别名: Insc; INSC_HUMAN; Inscuteable homolog (Drosophila); Protein inscuteable homolog.
分子量: 40/64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human INSC
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位:细胞浆
有丝分裂相关蛋白INSC抗体产品介绍:background: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. Tissue specificity:Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas. Function: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. 有丝分裂相关蛋白INSC抗体May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. Subunit: Interacts with ALS2CR19/PAR3-beta, F2RL2/PAR3, GPSM1/AGS3 and GPSM2/LGN. Subcellular Location: Cytoplasm. Note=Localizes to the apical cortex of mitotic epidermal cells and to the apical side of neuronal progenitor cells. Tissue Specificity: Isoform 1 is expressed 有丝分裂相关蛋白INSC抗体in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas. Database links: UniProtKB/Swiss-Prot: Q1MX18 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
有丝分裂相关蛋白INSC抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 细胞周期蛋白 细胞分化
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid