RAS家族关联结构域蛋白7抗体
规格：1mg/1ml
英文名： RASSF7
别名： C11orf13; Chromosome 11 open reading frame 13; HRAS1; HRAS1 related cluster 1; HRAS1 related cluster protein 1; HRC1; MGC126069; Ras association (RalGDS/AF 6) domain family (N terminal) member 7; Ras
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RASSF7
交叉反应：Human, Mouse, Rat, Cow, Horse, Sheep,
细胞定位：细胞浆
RAS家族关联结构域蛋白7抗体产品介绍：background: RASSF7 contains 1 Ras-associating domain. It is a centrosome-associated protein required to form a spindle and complete mitosis in the neural tube. There are two isoforms. Function: Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required forRAS家族关联结构域蛋白7抗体 the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. Subunit: Interacts with MAP2K7 and GTP-bound NRAS. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Note=Colocalizes with gamma-tubulin. Post-translational modifications: Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli. Similarity: Contains 1RAS家族关联结构域蛋白7抗体 Ras-associating domain. Database links: UniProtKB/Swiss-Prot: Q02833.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RAS家族关联结构域蛋白7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞分化 细胞类型标志物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid