纺锤体和着丝粒相关蛋白3抗体
规格：1mg/1ml
英文名： SKA3
别名： C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3.
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SKA3
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
纺锤体和着丝粒相关蛋白3抗体产品介绍：background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. Function: Component of the SKA1 complex, a microtubule-bindingsubcomplex of the outer kinetochore that is essential for properchromosome segregation. The SKA1 complex is a direct component ofthe kinetochore-microtubule interface and directly associates withmicrotubules as oligomeric assemblies. The complex facilitates theprocessive movement of microspheres along a microtubule in adepolymerization-coupled manner. In the complex纺锤体和着丝粒相关蛋白3抗体, it mediates themicrotubule-stimulated oligomerization. Subunit: Component of the SKA1 complex, composed of SKA1, SKA2 andSKA3. The core SKA1 complex is composed of 2 SKA1-SKA2heterodimers, each heterodimer interacting with a molecule of theSKA3 homodimer. The core SKA1 complex associates with microtubulesand forms oligomeric assemblies. Interacts directly with SKA1. Subcellula纺锤体和着丝粒相关蛋白3抗体r Location: Cytoplasm, cytoskeleton, spindle.Chromosome, centromere, kinetochore. Note=Localizes to the outerkinetochore and spindle microtubules during mitosis in a NDC80complex-dependent manner. Similarity: Belongs to the SKA3 family. Database links: UniProtKB/Swiss-Prot: Q8IX90.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
纺锤体和着丝粒相关蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid