单极纺锤体蛋白激酶1抗体
规格：1mg/1ml
英文名： MPS1
别名： Dual specificity protein kinase TTK; ECSTY kinase; ESK; FLJ38280; hMPS1; Monopolar Spindle 1 Like 1; Mps 1; Mps-1; MPS1L1; Phosphotyrosine Picked Threonine Kinase; PYT; TTK; TTK Protein Kinase; TTK_HU
分子量： 95kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MPS1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：
单极纺锤体蛋白激酶1抗体产品介绍：background: Mps1 (TTK) is a tyrosine and serine/threonine dual-specificity kinase required for centrosome duplication and the spindle checkpoint and has recently been shown to have a role in centrosome duplication. Alterations to Mps1 have been associated with cell transformation and chromosome instability in different tumor models. It is present in rapidly proliferating cell lines. Function: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential 单极纺锤体蛋白激酶1抗体for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. Tissue Specificity: Present in rapidly proliferating cell lines. Similarity: Belongs to the protein kinase superfamily. 单极纺锤体蛋白激酶1抗体Ser/Thr protein kinase family. Contains 1 protein kinase domain. Database links: UniProtKB/Swiss-Prot: P33981.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产单极纺锤体蛋白激酶1抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞周期蛋白 激酶和磷酸酶 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid