神经前体细胞表达蛋白1抗体
规格：1mg/1ml
英文名： NEDD1
别名： GCP WD; Neural precursor cell expressed, developmentally down regulated gene 1; TUBGCP7; FLJ35902; NEDD1_HUMAN.
分子量： 72kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NEDD1
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：细胞浆
神经前体细胞表达蛋白1抗体产品介绍：background: May play an important role during the embryonic development and differentiation of the central nervous system. Human NEDD1 localises to the centrosome and mitotic spindle. It binds to the components of the gamma-tubulin ring complex and target this complex to the centrosome and spindle. Function: Required for mitosis progression. Promotes thenucleation of microtubules from the spindle. Subunit: Interacts with FAM29A and gamma-tubulin. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Post-translational modifications: During mitosis, prior phosphorylation on Thr-550 by CDK1promotes subsequent phosphorylation神经前体细胞表达蛋白1抗体 by PLK1 on Thr-382, Ser-397,Ser-426 and Ser-637. Phosphorylated NEDD1 can interact withgamma-tubulin for targeting the gamma-tubulin ring complex (gTuRC)to the centrosome, an important step for spindle formation. Similarity: Contains 8 WD r神经前体细胞表达蛋白1抗体epeats. Database links: UniProtKB/Swiss-Prot: Q8NHV4.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经前体细胞表达蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 干细胞 细胞周期蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid