Rab蛋白GTP酶激活蛋白1抗体
规格：1mg/1ml
英文名： RABGAP1
别名： Rab GTPase-activating protein 1; Rab GAP1, GAP and centrosome associated protein; HSPC094; Rab GTPase activating protein 1; Rab6 GTPase activating protein GAPCenA; RBGP1_HUMAN.
分子量： 122kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RABGAP1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：细胞浆
Rab蛋白GTP酶激活蛋白1抗体产品介绍：background: Rab GTPase-activating protein 1 is a 1,069 amino acid cytoplasmic protein containing one PID domain and one Rab-GAP TBC domain. Rab GAP1 acts as a GTPase-activating protein of Rab 6A in the Rab 6A-mediated pathway, which is involved in the metaphase-anaphase transition. Expressed as four alternatively spliced variants, Rab GAP1 may also be involved in the microtubule nucleation by centrosome and in Golgi dynamics during the cell cycle. Rab GAP1 is encoded by a gene located on human chromosome 9, which consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Function: May act as a GTPase-activating protein of RAB6A. Mayplay a role in microtubule nucleation by centrosome. Mayparticipate in a RAB6A-mediated pathwayRab蛋白GTP酶激活蛋白1抗体 involved in themetaphase-anaphase transition. Subunit: Interacts with RAB6A and tubulin gamma. Subcellular Location: Cytoplasm, cytosol. Cytoplasm, cytoskeleton,centrosome. Note=Predominantly cytosolic but also associated withthe centrosome. Similarity: Contains 1 PID domain. Contains 1 Rab-GAP TBC domain. Gene ID: 23637 Database links: Entrez Gene: 519260 Cow Entrez Gene:Rab蛋白GTP酶激活蛋白1抗体 23637 Human Entrez Gene: 227800 Mouse Entrez Gene: 311911 Rat SwissProt: Q9Y3P9 Human SwissProt: A2AWA9 Mouse Unigene: 271341 Human Unigene: 383192 Mouse Unigene: 14944 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rab蛋白GTP酶激活蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 细胞类型标志物 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid