双特异性磷酸酶13抗体
规格：1mg/1ml
英文名： DUSP13
别名： BEDP; Branching enzyme interacting dual specificity protein phosphatase; Dual specificity phosphatase 13; Dual specificity phosphatase SKRP4; DUSP13A; DUSP13B; FLJ32450; MDSP; Muscle restricted dual s
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUSP13
交叉反应：Human, Mouse, Rat, Cow, Sheep,
细胞定位：
双特异性磷酸酶13抗体产品介绍：background: Members of the protein-tyrosine phosphatase superfamilycooperate with protein kinases to regulate cell proliferation anddifferentiation. This superfamily is separated into two familiesbased on the substrate that is dephosphorylated. One family, thedual specificity phosphatases (DSPs) acts on both phosphotyrosineand phosphoserine/threonine residues. This gene encodes differentbut related DSP proteins through the use of non-overlapping openreading frames, alternate splicing, and presumed differenttranscription promoters. Expression of the distinct proteins fromthis gene has been found to be tissue specific and the proteins maybe involved in postnatal development of specific tissues. A proteinencoded by the upstream ORF was found in skeletal muscle, whereasthe encoded protein from the downstream ORF was found only intestis. In mouse, a similar pattern of expression was found.Multiple alternatively spliced transcript variants were described,but the full-length sequence of only some were determined.[provided by RefSeq, Jul 2008]. Function: May be involved in the regulation双特异性磷酸酶13抗体 of meiosis and/ordifferentiation of testicular germ cells during spermatogenesis.Exhibits intrinsic phosphatase activity towards bothphospho-seryl/threonyl and -tyrosyl residues of myelin basicprotein, with similar specific activities in vitro. Tissue Specificity: Most abundantly expressed in the testis. Alsofound in the skeletal muscle. Testis-specific (at protein level). Similarity: Belongs to the protein-tyrosine双特异性磷酸酶13抗体 phosphatase family.Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: UniProtKB/Swiss-Prot: Q9UII6.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双特异性磷酸酶13抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导 细胞周期蛋白 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid