微原纤维胶原相关蛋白1抗体
规格:1mg/1ml
英文名: MFAP1
别名: MFAP1 is an extracellular protein associated with elastic fiber microfibrils.
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MFAP1
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位:细胞外基质 分泌型蛋白
微原纤维胶原相关蛋白1抗体产品介绍:background: Microfibrils are an important component of the extracellular matrix of many tissues and can either associate with or without elastin. Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically 微原纤维胶原相关蛋白1抗体recognizable multiple congenital anomaly/mental retardation syndrome. Function: Component of the elastin-associated microfibrils. Subcellular Location: Secreted, extracellular space, extracellular matrix. Similarity: Belongs to the MFAP1 family.微原纤维胶原相关蛋白1抗体 Database links: Entrez Gene: 510905 Cow Entrez Gene: 4236 Human Entrez Gene: 100034361 Mouse Entrez Gene: 67532 Mouse Omim: 600215 Human SwissProt: 5EA98 Cow SwissProt: P55081 Human SwissProt: Q9CQU1 Mouse Unigene: 61418 Human Unigene: 270393 Mouse Unigene: 440764 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产微原纤维胶原相关蛋白1抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid