染色体相关蛋白H抗体
规格：1mg/1ml
英文名： CAPH
别名： Barren Drosophila Homolog of 1; Barren homolog protein 1; BRRN; CAP H; CAPH; Chromosome associated protein H; Condensin complex subunit 2; Condensin subunit 2; Condesin; HCAP H; mCAP H; NCAPH; Non SMC
分子量： 82kD
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BRRN1/CA
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
染色体相关蛋白H抗体产品介绍：background: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Subunit: Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and染色体相关蛋白H抗体 NCAPG. Subcellular Location: CNucleus. Cytoplasm. Chromosome. Tissue Specificity: Widely expressed at low level. Expressed in proliferating cells. Post-translational modifications: Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin complex and is required for chromosome condensation (By similarity). Similarity: Belongs to the CND2 (condensin subunit 2)染色体相关蛋白H抗体 family. Database links: UniProtKB/Swiss-Prot: Q15003.3 Entrez Gene: 23397 Human Entrez Gene: 215387 Mouse Omim: 602332 Human SwissProt: Q15003 Human SwissProt: Q8C156 Mouse Unigene: 308045 Human Unigene: 29786 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
染色体相关蛋白H抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid