细胞分裂周期蛋白CDC123抗体
规格：1mg/1ml
英文名： CDC123
别名： C10orf7; CD123_HUMAN; CDC123; Cell division cycle protein 123 homolog; D123; HT 1080; HT-1080; Protein D123; PZ32.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CDC123/C
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
细胞分裂周期蛋白CDC123抗体产品介绍：background: Required for S phase entry of the cell cycle.The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents细胞分裂周期蛋白CDC123抗体 the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers. Function: Required for S phase entry of the cell cycle Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes细胞分裂周期蛋白CDC123抗体 with the highest expression in testis. Similarity: Belongs to the CDC123 family. Database links: UniProtKB/Swiss-Prot: O75794.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞分裂周期蛋白CDC123抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞周期蛋白 激酶和磷酸酶 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit