细胞分裂周期调控蛋白45抗体
规格：1mg/1ml
英文名： CDC45L
别名： CDC 45; CDC 45L; CDC45 (cell division cycle 45, S.cerevisiae homolog) like; CDC45; CDC45 cell division cycle 45 like; CDC45 like; CDC45 related protein; CDC45_HUMAN; CDC45L2; Cell division control pro
分子量： 66kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CDC45L
交叉反应：Human, Mouse, Rat, Pig, Horse,
细胞定位：细胞核 细胞浆
细胞分裂周期调控蛋白45抗体产品介绍：background: The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. 细胞分裂周期调控蛋白45抗体Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Function: Required for initiation of chromosomal DNA replication.< Subunit: Associated with ORC2. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity细胞分裂周期调控蛋白45抗体: Widely expressed, highest levels are found in ***** testis and thymus and in fetal liver. Similarity: Belongs to the CDC45 family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产细胞分裂周期调控蛋白45抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid