细胞分化蛋白SEPT10抗体
规格：1mg/1ml
英文名： 42623
别名： SEPT 10; SEPT-10; Septin 10; Septin-10; Septin 10; SEP10_HUMAN.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SEPT10
交叉反应：Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit,
细胞定位：细胞浆
产细胞分化蛋白SEPT10抗体品介绍：background: The SEPT10 gene encodes a member of the septin family of cytoskeletal proteins which have GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms. Function: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Note=Using a GFP-fusion protein, detected in the nucleus (PubMed:12711328). Tissue Specificity:细胞分化蛋白SEPT10抗体 Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines. Similarity: Belongs to the septin family. Gene ID: 151011 Database links: Entrez Gene: 151011 Human Entrez Gene: 细胞分化蛋白SEPT10抗体103080 Mouse Omim: 611737 Human SwissProt: Q9P0V9 Human SwissProt: Q8C650 Mouse Unigene: 469615 Human Unigene: 346842 Mouse Unigene: 397041 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SEPTIN(SEPT)家族是细胞骨架蛋白的一种，具有GTPase的活性。经研究发現，SEPT参与细胞核分裂、细胞膜的运输以及构成细胞骨架。
细胞分化蛋白SEPT10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid