腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1抗体
规格：1mg/1ml
英文名： BS69
别名： Adenovirus 5 E1A binding protein; Bone morphogenetic protein receptor associated molecule 1; BRAM1; BS69 variant 1; BS69 variant 2; BS69 variant 3; BS69 variant 4; Zinc finger MYND domain containing 1
分子量： 71kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Adenovir
交叉反应：Human, Mouse, Rat, Chicken, Dog, Horse, Sheep,
细胞定位：细胞核
腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1抗体产品介绍：background: The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Function: Corepressor of transcription (Probable). May be involved in chromatin remodeling through association with several remodeling factors. Subunit: Interacts (via MYND-type zinc finger) with NCOR1. Interacts (via MYND-type zinc finger) with human adenovirus early E1A protein (via PXLXP motif); this interaction inhibits E1A mediated transactivation. Interacts (via MYND-type zinc finger) with Epstein-Barr virus EBNA2 protein (via PXLXP motif). Interacts (via MYND-type zinc finger) with EZH2. Interacts with E2F6. Subcellular Location: Nucleus. Chromosome. 腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1抗体Note=Associates with chromatin and mitotic chromosomes. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Ubiquitinated, leading to proteasomal degradation. Similarity: Contains 1 bromo domain. Contains 1 MYND-type zinc finger. Contains 1 PHD-type zinc finger. Contains 1 PWWP domain. Gene ID: 10771 Database links: Entrez Gene: 10771 Human Entrez Gene: 66505 Mouse Entrez Gene: 291259 Rat GenBank: NP_006615 Human GenBank: NP_腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1抗体997644 Human Omim: 608668 Human SwissProt: Q15326 Human SwissProt: Q8R5C8 Mouse Unigene: 292265 Human Unigene: 397307 Mouse Unigene: 38301 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
腺病毒5结合蛋白BS69/骨形态发生蛋白受体相关分子1抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid