神经生长因子受体相关蛋白1抗体
规格：1mg/1ml
英文名： NGFRAP1
别名： NADE; BEX3; BEX3_HUMAN; Brain expressed X linked 3 (mouse) homolog; Brain-expressed X-linked protein 3; Nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor assoc
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NADE/NGF
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
神经生长因子受体相关蛋白1抗体产品介绍：background: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases. Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver. Function: May be a signaling adapter molecule involved inp75NTR-mediated apoptosis induced by NGF. Plays a role inzinc-triggered neuronal death (By similarity). May play animportant role in the pathogenesis of neurogenetic diseases. Subunit: Self-associates. Interacts with 14-3-3神经生长因子受体相关蛋白1抗体 epsilon (YWHAE).Interacts with DIABLO/SMAC (By similarity). Binds to the DEATHdomain of p75NTR/NGFR. Subcellular Location: Nucleus. Cytoplasm. Note=Shuttles betweenthe cytoplasm and the nucleus. Associates with replicatingmitochondria (By similarity). Tissue Specificity: Found in ovarian granulosa cells, testis,prostate and seminal vesicle tissue. High levels also detected inliver. Post-translational 神经生长因子受体相关蛋白1抗体modifications: Ubiquitinated. Degraded by the proteasome (By similarity). Similarity: Belongs to the BEX family. Gene ID: 27018 Database links: Entrez Gene: 27018 Human Entrez Gene: 12070 Mouse Omim: 300361 Human SwissProt: Q00994 Human SwissProt: Q9WTZ9 Mouse Unigene: 448588 Human Unigene: 90787 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经生长因子受体相关蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞凋亡 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid