死亡结构域蛋白NRH2抗体
规格：1mg/1ml
英文名： NRH2
别名： NRADD; PLAIDD; NRADD_RAT; Death domain-containing membrane protein NRADD; Neurotrophin receptor homolog-2; NRH2; Neurotrophin receptor-alike death domain protein; P75-like apoptosis-inducing death dom
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from rat NRH2
交叉反应：Mouse, Rat, Dog, Pig, Horse, Sheep,
细胞定位：细胞核 细胞膜
死亡结构域蛋白NRH2抗体产品介绍：background: A single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis. Function: Modulates NTRK1 signaling. Can activate severalintracellular signaling pathways, leading to activation of JUN.Promotes translocation of SORT1 to the cell membrane, and therebyhinders lysosomal degradation of SOTR1 and promotes its interactionwith NGFR (By similarity). Both isoform 1 and isoform 2 promoteapoptosis. Subunit: Interacts with NTRK1 (By similarity). Isoform 1 andisoform 2 interact with NGFR. Interacts with SORT1. Subcellular Location: Cell membrane; Single-pass type III membraneprotein. Nucleus死亡结构域蛋白NRH2抗体 (By similarity). Note=Proteolytic processing givesrise to an intracellular domain that translocates to the nucleus(By similarity). Tissue Specificity: Detected in embryo, including embryonic brain.Detected at very low levels in ***** testis, spleen, thymus andlung. Post-translational modifications: Isoform 1 is N-glycosylated. Isoform 2 is not N-glycosylated. Similarity: Contains 1 death domain. Gene ID: 死亡结构域蛋白NRH2抗体246143 Database links: UniProtKB/Swiss-Prot: Q8K5A9.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
死亡结构域蛋白NRH2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid