前细胞胀亡受体诱导膜损伤蛋白抗体
规格：1mg/1ml
英文名： Porimin
别名： KCT3; Keratinocytes associated transmembrane protein 3; Pro oncosis receptor inducing membrane injury; Serine/threonine rich receptor; TMEM123; Transmembrane protein 123; PORIM_HUMAN.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Porimin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞膜
前细胞胀亡受体诱导膜损伤蛋白抗体产品介绍：background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. Function: Implicated in 前细胞胀亡受体诱导膜损伤蛋白抗体oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Ubiquitous. Not expressed in ovary前细胞胀亡受体诱导膜损伤蛋白抗体. Expressed in keratinocytes. Similarity: Belongs to the CD164 family. Gene ID: 114908 Database links: Entrez Gene: 114908 Human Omim: 606356 Human SwissProt: Q8N131 Human SwissProt: Q96QV2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前细胞胀亡受体诱导膜损伤蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 激酶和磷酸酶 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid