血型抗原前体蛋白抗体
规格:1mg/1ml
英文名: Blood Group Antigen Precursor
别名: A transferase; Abo; ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase); ABO glycosyltransferase; B (A) alpha 1, 3 glactosyltransf
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Blood Gr
交叉反应:Chimpanzee,
细胞定位:细胞浆 细胞膜 分泌型蛋白
血型抗原前体蛋白抗体产品介绍:background: This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. Function: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the血型抗原前体蛋白抗体 B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. Post-translational modifications: The soluble form derives from the membrane form by proteolytic processing. Similarity: Belongs to the glycosyltransferase 6 family. Gene ID: 28 Database links: Entrez Gene: 28 Human Entrez Gene: 80908 Mouse Entrez Gene: 65270 Rat Omim: 110300 Human 血型抗原前体蛋白抗体SwissProt: P16442 Human SwissProt: P38649 Mouse SwissProt: Q9ET32 Rat Unigene: 654423 Human Unigene: 160386 Mouse Unigene: 112591 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血型抗原前体蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid