凯尔血型糖蛋白CD238抗体
规格：1mg/1ml
英文名： CD238
别名： CD238; CD238 antigen; ECE3; kel; Kell blood group; Kell blood group glycoprotein; Kell blood group metallo endopeptidase; Kell blood group metalloendopeptidase; KELL NULL; Kell protein; KELL_HUMAN.
分子量： 83kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Blood Gr
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆 细胞膜
凯尔血型糖蛋白CD238抗体产品介绍：background: This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. Function: Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. Subunit: Heterodimer with XK; disulfide-linked. Subcellular Location: Cell membrane; Single-pass type II membrane protein. Note=Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton. Tissue Specificity: Expressed at high levels in erythrocytes and testis 凯尔血型糖蛋白CD238抗体(in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many ***** and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow. Post-translational modifications: N-glycosylated. Similarity: Belongs to the peptidase M13 family. Gene ID: 3792 Database links: Entrez Gene: 3792 Human Omim: 凯尔血型糖蛋白CD238抗体110900 Human SwissProt: P23276 Human Unigene: 368588 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凯尔血型糖蛋白CD238抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid