垂体瘤细胞凋亡抗体
规格:1mg/1ml
英文名: RHBDD3
别名: C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3.
分子量: 40kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RHBDD3 (
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
垂体瘤细胞凋亡抗体产品介绍:background: PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG. Subcellular Location: Membrane; Multi-pass membrane protein垂体瘤细胞凋亡抗体 (Potential). Similarity: Contains 1 UBA domain Database links: Entrez Gene: 25807 Human Entrez Gene: 279766 Mouse Entrez Gene: 289753 Rat SwissProt: Q9Y3P4 Human SwissProt: Q8BP97 Mouse SwissProt: Q642B3 Rat Unigene: 106730 Human Unigene: 260866 Mouse Unigene: 9606 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or 垂体瘤细胞凋亡抗体diagnostic applications. RHBDD3分子是一个全新的TLR信号途径的负向调控蛋白分子,是一个能够显著抑制自身**性**发生的效应分子,RHBDD3控制机体避免发生过度的**应答、防止自身**性**的发生具有重要意义。
产垂体瘤细胞凋亡抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞凋亡 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit