硫氧还蛋白5抗体
规格:1mg/1ml
英文名: TXNDC5
别名: EndoPDI; Endoplasmic reticulum protein ERp46; Endothelial protein disulphide isomerase; ERP46; Hcc 2; PDIA15; Protein disulfide isomerase family A member 15; Thioredoxin domain containing 5 (endoplasm
分子量: 44kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TXNDC5 (
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:细胞浆
硫氧还蛋白5抗体产品介绍:background: TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to硫氧还蛋白5抗体 the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details. Function: Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast Subcellular Location: Endoplasmic硫氧还蛋白5抗体 reticulum lumen Similarity: Belongs to the protein disulfide isomerase family. Contains 3 thioredoxin domains. Database links: UniProtKB/Swiss-Prot: Q8NBS9.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硫氧还蛋白5抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞凋亡
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid