甲胎蛋白调节蛋白1抗体
规格:1mg/1ml
英文名: ZHX2
别名: AFP regulator 1; AFR1; Alpha fetoprotein regulator 1; RAF; Regulator of AFP; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; ZHX2_HUMAN.
分子量: 92kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZHX2/Alp
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位:
甲胎蛋白调节蛋白1抗体产品介绍:background: The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008].[FUNCTION] Acts as a transcriptional repressor.[SUBUNIT] Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.[SUBCELLULAR LOCATION] Nucleus. [TISSUE SPECIFICITY] Ubiquitously expressed. [SIMILARITY] Belongs to甲胎蛋白调节蛋白1抗体 the ZHX family. Function: Acts as a transcriptional repressor. Subunit: Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the ZHX family. Contains 2 C2H2-type zinc fingers. Contains 4 homeobox 甲胎蛋白调节蛋白1抗体DNA-binding domains. Database links: UniProtKB/Swiss-Prot: Q9Y6X8.1 Entrez Gene: 22882 Human Omim: 609185 Human SwissProt: Q9Y6X8 Human Unigene: 377090 Human Unigene: 658443 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甲胎蛋白调节蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 转录调节因子 锌指蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid