肌浆网钙ATP酶1/内质网钙ATP酶1抗体
规格：1mg/1ml
英文名： AT2A1/SERCA1 ATPase
别名： fast twitch skeletal muscle isoform; AT2A1_HUMAN; ATP2A; ATP2A1; ATPase Ca++ transporting cardiac muscle fast twitch 1; ATPase Ca++ transporting fast twitch 1; ATPase, Ca(2+)-transporting fast twitch
分子量： 110kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SERCA1 A
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
肌浆网钙ATP酶1/内质网钙ATP酶1抗体产品介绍：background: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Subunit: Associated with sarcolipin (SLN) and phospholamban (PLN) (By similarity). Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Skeletal 肌浆网钙ATP酶1/内质网钙ATP酶1抗体muscle, fast twitch muscle (type II) fibers. DISEASE: Defects in ATP2A1 are the cause of Brody myopathy (BRM) [MIM:601003]. An autosomal recessive myopathy characterized by increasing impairment of relaxation of fast twist skeletal muscle during exercise. Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. Database links: Entrez Gene: 518117 Cow Entrez Gene: 487 Human Entrez Gene: 11937 Mouse Entrez Gene: 100037716 Rabbit Entrez Gene: 116601 Rat Omim: 108730 Human SwissProt肌浆网钙ATP酶1/内质网钙ATP酶1抗体: Q0VCY0 Cow SwissProt: O14983 Human SwissProt: Q8R429 Mouse SwissProt: P04191 Rabbit SwissProt: Q64578 Rat Unigene: 657344 Human Unigene: 35134 Mouse Unigene: 217139 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌浆网钙ATP酶1/内质网钙ATP酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 信号转导 转录调节因子 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid