原始广泛存在蛋白1抗体
规格：1mg/1ml
英文名： AUP1
别名： AA589454; AUP 1; AUP1; AUP1_HUMAN; Ancient ubiquitous protein 1.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AUP1/Anc
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
原始广泛存在蛋白1抗体产品介绍：background: Ancient ubiquitous protein 1 (AUP1) contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. It has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. Function: May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. Subunit: Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1. Interacts with the cytoplasmic tai原始广泛存在蛋白1抗体l of ITGA2B, ITGA1, ITGA2, ITGA5, ITGAV and ITGAM. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side. Tissue Specificity: Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain. Similarity: Belongs to the AUP1 family. Contains 1 CUE domain. Gene ID: 原始广泛存在蛋白1抗体550 Database links: Entrez Gene: 550 Human Entrez Gene: 11993 Mouse Entrez Gene: 680423 Rat Omim: 602434 Human SwissProt: Q9Y679 Human SwissProt: P70295 Mouse SwissProt: A1L134 Rat Unigene: 411480 Human Unigene: 386752 Mouse Unigene: 198163 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原始广泛存在蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid