血小板反应蛋白2/凝血酶敏感蛋白2抗体
规格:1mg/1ml
英文名: Thrombospondin 2
别名: THBS2; Thrombospondin-2; Thrombospondin2; TSP2; TSP2_HUMAN.
分子量: 128kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Thrombos
交叉反应:Human, Mouse, Rat, Horse,
细胞定位:
血小板反应蛋白2/凝血酶敏感蛋白2抗体产品介绍:background: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Function: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Subunit: Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Tissue Specificity: High expression in invertebral disk tissue. DISEASE: Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:603932]; 血小板反应蛋白2/凝血酶敏感蛋白2抗体also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain. Similarity: Belongs to the thrombospondin family. Contains 血小板反应蛋白2/凝血酶敏感蛋白2抗体2 EGF-like domains. Contains 1 laminin G-like domain. Contains 1 TSP C-terminal (TSPC) domain. Contains 3 TSP type-1 domains. Contains 8 TSP type-3 repeats. Contains 1 VWFC domain. Database links: UniProtKB/Swiss-Prot: P35442.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板反应蛋白2/凝血酶敏感蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 细胞因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid