胰岛素基因增强结合蛋白1抗体
规格:1mg/1ml
英文名: Islet 1
别名: Insulin gene enhancer protein ISL 1; Insulin gene enhancer protein ISL-1; Insulin related protein; Isl 1; ISL LIM homeobox 1; ISL1; ISL1 transcription factor LIM homeodomain; ISL1 transcription factor
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Islet 1
交叉反应:Human, Mouse, Rat, Chicken, Horse, Sheep,
细胞定位:细胞核
胰岛素基因增强结合蛋白1抗体产品介绍:background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq胰岛素基因增强结合蛋白1抗体, Jul 2008] Function: Binds to one of the cis-acting domain of the insulin gene enhancer. Subcellular Location: Nucleus. Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. Similarity: Contains 1 homeobox DNA-binding domain. Contains 2 LIM zinc-binding domains. Gene ID: 3670 Database links: Entrez Gene: 396383 Chicken Entrez Gene: 3670 Human Entrez Gene: 16392 Mouse Entrez Gene: 64444 Rat Entrez Gene: 胰岛素基因增强结合蛋白1抗体30147 Zebrafish Omim: 600366 Human SwissProt: P50211 Chicken SwissProt: P61371 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛素基因增强结合蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 发育生物学 神经生物学 信号转导 干细胞 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid