过氧化物酶体增殖物激活受体γ辅激活子1β抗体
规格：1mg/1ml
英文名： PGC1 beta
别名： PERC; peroxisome proliferative activated receptor, gamma, coactivator 1,; peroxisome proliferator-activated receptor gamma coactivator 1 beta; Peroxisome proliferator-activated receptor gamma coactiva
分子量： 113kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PGC1 bet
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig,
细胞定位：
过氧化物酶体增殖物激活受体γ辅激活子1β抗体产品介绍：background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle. Function: Plays a role of stimulator of transcription factors andnuclear receptors activities. Activates transcritional activity ofestrogen receptor过氧化物酶体增殖物激活受体γ辅激活子1β抗体 alpha, nuclear respiratory factor 1 (NRF1) andglucocorticoid receptor in the presence of glucocorticoids. Mayplay a role in constitutive non-adrenergic-mediated mitochondrialbiogenesis as suggested by increased basal oxygen consumption andmitochondrial number when overexpressed. May be involved in fatoxidation and non-oxidative glucose metabolism and in theregulation of energy expenditure. Subunit: Interacts with hepatocyte nuclear factor 4-alpha/HNF4A,Sterol regulatory binding transcription factor 1/SREBF1,PPAR-alpha/PPARA, thyroid hormone receptor beta/THRB and host cellfactor/HCFC1. Interacts with estrogen-related receptor gamma/ESRRGand alpha/ESRRA. Interacts with PRDM16 (By similarity). Interactswith estrogen receptor alpha/ESR1. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous with higher 过氧化物酶体增殖物激活受体γ辅激活子1β抗体expression in heart,brain and skeletal muscle. Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: UniProtKB/Swiss-Prot: Q86YN6.2 Entrez Gene: 133522 Human Entrez Gene: 170826 Mouse Entrez Gene: 291567 Rat Omim: 608886 Human SwissProt: Q86YN6 Human SwissProt: Q8VHJ7 Mouse SwissProt: Q811R2 Rat Unigene: 483816 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
过氧化物酶体增殖物激活受体γ辅激活子1β抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 信号转导 糖尿病 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid