沉默调节相关蛋白4抗体
规格:1mg/1ml
英文名: SIRT4
别名: NAD dependent deacetylase sirtuin 4; NAD-dependent ADP-ribosyltransferase sirtuin-4; Silent mating type information regulation 2 homolog; Sir 2 like 4; SIR 2 like protein 4; Sir2 like 4; SIR2 like pro
分子量: 32kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SIRT4
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
细胞定位:细胞浆
沉默调节相关蛋白4抗体产品介绍:background: NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. Function: NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. Subunit: Interacts with GLUD1, IDE and SLC25A5. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level).沉默调节相关蛋白4抗体 Widely expressed. Weakly expressed in leukocytes and fetal thymus. Similarity: Belongs to the sirtuin family. Class II subfamily. Contains 1 deacetylase sirtuin-type domain. Gene ID: 23409 Database links: Entrez Gene: 519328 Cow Entrez Gene: 23409 Human Entrez Gene: 75387 Mouse Entrez Gene: 100125349 Pig Entrez Gene: 304539 Rat Omim: 604482 Human SwissProt: Q1JQC6 Cow SwissProt: Q9Y6E7 Human沉默调节相关蛋白4抗体 SwissProt: Q8R216 Mouse Unigene: 50861 Human Unigene: 332616 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
沉默调节相关蛋白4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 信号转导 糖尿病 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid