激活增强子结合蛋白2ε抗体
规格:1mg/1ml
英文名: TFAP2E
别名: Activating enhancer binding protein 2 epsilon; Activating enhancer-binding protein 2-epsilon; Adaptor related protein complex 2 epsilon subunit; AP 2E; AP2 epsilon; AP2-epsilon; AP2E; AP2E_HUMAN; MGC4
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TFAP2E
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
激活增强子结合蛋白2ε抗体产品介绍:Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation. Subcellular Location: Nucleus. Tissue Specificity: Expressed in skin, primary keratinocytes, 激活增强子结合蛋白2ε抗体immortalized keratinocytes, and HeLa cell line. Similarity: Belongs to the AP-2 family. Database links: Entrez Gene: 339488 Human Entrez Gene: 332937 Mouse Entrez Gene: 313596 Rat Omim: 614428 Human SwissProt: Q6VUC0 Human SwissProt: Q6VUP9 Mouse Unigene: 567844 Human Unigene: 331881 Mouse Unigene: 231431 Rat Important Note: This product as supplied is intended for research use only,激活增强子结合蛋白2ε抗体 not for use in human, therapeutic or diagnostic applications.
激活增强子结合蛋白2ε抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid