TBX18蛋白抗体
规格：1mg/1ml
英文名： TBX18
别名： T box 18; T box protein 18; T box transcription factor TBX18; T-box protein 18; T-box transcription factor TBX18; TBX18; TBX18_HUMAN.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TBX18
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞核
TBX18蛋白抗体产品介绍：background: This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] Function: Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter TBX18蛋白抗体and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area. Subunit: Homodimer. Can form a heterodimer with TBX15. Interacts with GATA4 AND NKX2-5. Interacts (via engrailed homology 1 repressor motif) with TLE3; this interaction represses TBX18 transcriptional activity. Interacts with PAX3. Subcellular Location: Nucleus. Similarity: Contains 1 T-box DNA-binding domain.TBX18蛋白抗体 Gene ID: 9096 Database links: Entrez Gene: 9096 Human Entrez Gene: 76365 Mouse Entrez Gene: 315870 Rat Omim: 604613 Human SwissProt: O95935 Human SwissProt: Q9EPZ6 Mouse Unigene: 251830 Human Unigene: 158789 Mouse Unigene: 161921 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
TBX18蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid