Toll样蛋白受体10抗体
规格：1mg/1ml
英文名： TLR10/CD290
别名： CD 290; CD 290 antigen; CD290; CD290 antigen; MGC104967; MGC126398; MGC126399; OTTHUMP; OTTHUMP; TLR10; TLR10_HUMAN; Toll like receptor 10; Toll-like receptor 10; TLR10 toll-like
分子量： 92kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TLR10
交叉反应：Human, Rat, Cow, Horse, Sheep,
细胞定位：细胞膜
Toll样蛋白受体10抗体产品介绍：background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. MultipleToll样蛋白受体10抗体 alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010] Function: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Tissue Specificity: Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines. Similarity: Belongs to the Toll-like receptor family. Contains 15 LRRToll样蛋白受体10抗体 (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 TIR domain. Gene ID: 81793 Database links: Entrez Gene: 81793 Human Omim: 606270 Human SwissProt: Q9BXR5 Human Unigene: 120551 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Toll样蛋白受体10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞膜受体 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid