骨骼肌肌特异性肌钙蛋白T-SS抗体
规格：1mg/1ml
英文名： Troponin T-Slow Skeletal
别名： Troponin T-SS; Cardiac muscle troponin T-Slow Skeletal; Cardiac Troponin T-Slow Skeletal; TNNT1_HUMAN.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Troponin
交叉反应：Human,
细胞定位：
产骨骼肌肌特异性肌钙蛋白T-SS抗体品介绍：background: Actin is a highly conserved protein that is expressed in all eukaryotic cells and interacts with Myosin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between Actin and Myosin by binding to calcium. Troponin is made up of at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Structures of skeletal muscle Troponin are composed of Troponin C (the sensor), Troponin I (the regulator) and three Troponin T (the link to the muscle thin filament) proteins, one of which functions as a Tropomyosin-binding protein and is known as Troponin T-SS (Troponin T-Slow Skeletal). Defects in the gene encoding Troponin T-SS are the cause of nemaline 骨骼肌肌特异性肌钙蛋白T-SS抗体myopathy type 5 (NEM5), a form of nemaline myopathy characterized by mild contractures of the shoulders and hips, tremors and respiratory problems that often lead to death. Troponin T-SS is expressed as three isoforms due to alternative splicing events. Function: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to 骨骼肌肌特异性肌钙蛋白T-SS抗体striated muscle actomyosin ATPase activity. Similarity: Belongs to the troponin T family. Gene ID: 7138 Database links: Entrez Gene: 7138 Human Omim: 191041 Human SwissProt: P13805 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骨骼肌肌特异性肌钙蛋白T-SS抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid