CBX7蛋白抗体
规格：1mg/1ml
英文名： CBX7
别名： CBX-7; CBX7_HUMAN; Cbx 7; CBX7; Chromobox homolog 7; Chromobox protein homolog 7; OTTHUMP.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CBX7
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee,
细胞定位：细胞核
CBX7蛋白抗体产品介绍：background: Control of cell proliferation by Polycomb group proteins (PcG) is an important facet of cellular homeostasis and its disruption can promote tumorigenesis. CBX7 is a novel PcG protein which is found to control the growth of normal cells. CBX7 is a gene that encodes a Polycomb protein, as shown by sequence homology, its interaction with Ring1 and its localization to nuclear Polycomb bodies. CBX7 extends the lifespan of a wide range of normal human cells and immortalizes mouse fibroblasts by downregulating expression of the Ink4a/Arf locus. CBX7 does not inter-function or colocalize with Bmi1, and both can exert their actions independently of each other as shownCBX7蛋白抗体 by reverse genetics. CBX7 was highly expressed in three different prostate cancer cell lines and present at elevated levels in normal prostate. (Gil et al., 2004). Subcellular Location: Nuclear Similarity: Contains 1 chromo domain. Gene ID: 23492 Database links: Entrez Gene: 23492 Human Entrez Gene: 525770 Cow Entrez Gene: 52609 Mouse Entrez Gene: 362962 Rat Omim: 608457 Human SwissProt: O95931 CBX7蛋白抗体Human SwissProt: Q8VDS3 Mouse SwissProt: P60889 Rat Unigene: 356416 Human Unigene: 12512 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CBX7蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转运蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid