肿瘤相关糖蛋白72抗体
规格：1mg/1ml
英文名： TAG72
别名： CA 72.4; TAG 72; Tumor associated Glycoprotein 72.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TAG72
交叉反应：Human,
细胞定位：细胞核 细胞浆
肿瘤相关糖蛋白72抗体产品介绍：background: The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas. Function: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex,肿瘤相关糖蛋白72抗体 the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Subunit: Binds TAF5 and TAF6.肿瘤相关糖蛋白72抗体 Component of TFIID and the TATA-binding protein-free TAF complex (TFTC). TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Binds N-terminal domain of p53/TP53 which is essential for transcription. Subcellular Location: Cytoplasmic. Similarity: Belongs to the TAF9 family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产肿瘤相关糖蛋白72抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid